Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384806 | 1.00 | TEK (0.46) | TEKALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL21165735 | 0.89 | KMT2A (0.40) | TEKLMNAMAPTHTTCYP11B2 | |
| SCHEMBL17384819 | 0.85 | EGFR (0.48) | TEKMAPTL3MBTL1CYP11B2EGFR | |
| SCHEMBL17822333 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10CYP2C19SMN1; SMN2 | |
| SCHEMBL30337202 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10CYP2C19SMN1; SMN2 | |
| SCHEMBL17385205 | 0.79 | ALDH1A1 (0.44) | TEKALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL19103283 | 0.78 | EGFR (0.41) | TEKALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL17384807 | 0.77 | EGFR (0.53) | L3MBTL1EGFRKMT2A | |
| SCHEMBL822744 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10CYP2C19SMN1; SMN2 | |
| SCHEMBL19103280 | 0.74 | KDM4E (0.47) | ALDH1A1HSD17B10MAPTHPGDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |