SCHEMBL30337651

SCHEMBL30337651

CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NC(=O)Nc3ccc(Cl)cn3)C2=O)c(F)c1

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 11/20 0.80
FPR1 P21462 8/20 0.80
F10 P00742 9/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18964313 1.00 FPR2 (0.80) FPR2FPR1F10
SCHEMBL4683510 0.91 F10 (0.70) FPR2FPR1F10
SCHEMBL21898911 0.90 FPR2 (0.82) FPR2FPR1
SCHEMBL30337623 0.89 FPR2 (1.00) FPR2FPR1F10
SCHEMBL18964281 0.89 FPR2 (1.00) FPR2FPR1F10
SCHEMBL18964535 0.89 FPR2 (0.88) FPR2FPR1F10
SCHEMBL30337558 0.89 FPR2 (0.88) FPR2FPR1F10
SCHEMBL18964046 0.89 FPR2 (0.88) FPR2FPR1F10
SCHEMBL30337638 0.87 FPR2 (0.82) FPR2FPR1F10
SCHEMBL18955164 0.87 FPR2 (0.82) FPR2FPR1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110996950-B Piperidinone formyl peptide 2 receptor agonists and formyl peptide 1 receptor agonists 百时美施贵宝公司 2023-04-04 CN disclosed