Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234490 | 0.83 | SCN9A (0.35) | SCN9AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23883828 | 0.82 | SCN9A (0.39) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL23883735 | 0.81 | SCN9A (0.42) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL23883696 | 0.81 | SCN9A (0.40) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL23883622 | 0.80 | SCN9A (0.43) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL30176308 | 0.79 | AS3MT (0.47) | SCN9ARORCALDH1A1CNR2CNR1 | |
| SCHEMBL23886826 | 0.79 | AS3MT (0.47) | SCN9ARORCALDH1A1CNR2CNR1 | |
| SCHEMBL28995442 | 0.78 | SCN9A (0.40) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL23884077 | 0.77 | SCN9A (0.39) | SCN9ARORCHTR1ASLC6A2SLC6A4 | |
| SCHEMBL23883771 | 0.77 | SCN9A (0.37) | SCN9ARORCHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916749-A | Substituted 5-hydroxyindole compounds as alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |