⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100731 | 1.00 | — | — | |
| Methane SCHEMBL27908574 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL8576872 | 0.82 | CYP1A2 (0.44) | — | |
| SCHEMBL1966377 | 0.79 | TSHR (0.41) | — | |
| SCHEMBL8488017 | 0.79 | CYP1A2 (0.42) | — | |
| SCHEMBL2818597 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL57480 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL29352197 | 0.78 | TSHR (0.63) | — | |
| Water SCHEMBL19410621 | 0.78 | TSHR (0.63) | — | |
| Water SCHEMBL27896186 | 0.78 | TSHR (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| CN-119053551-A | Nano iron phosphide particles, composite containing nano iron phosphide particles and reduction catalyst | 国立大学法人大阪大学 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-115835866-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-03-21 | — | — | CN | disclosed |