SCHEMBL1966377

SCHEMBL1966377

N#Cc1cccc(S)c1S

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TRPV4 Q9HBA0 3/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MCL1 Q07820 1/20 0.35
HTT P42858 1/20 0.35
MAP2K1 Q02750 1/20 0.33
USP8 P40818 1/20 0.33
USP7 Q93009 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3058843 0.87 TSHR (0.46) TSHRCA1CA2TRPV4MAOA
SCHEMBL100731 0.79
SCHEMBL30338255 0.79
SCHEMBL3074213 0.78 MAOA (0.45) TSHRCA1CA2TRPV4MAOA
Methane SCHEMBL27908574 0.77 TSHR (0.48) TSHRCA1CA2TRPV4MCL1
SCHEMBL15252030 0.76 TSHR (0.48) TSHRCA1CA2TRPV4MAOA
SCHEMBL31287954 0.76 TSHR (0.60) TSHRCA1CA2MAOAMAOB
SCHEMBL2642647 0.76 TRPV4 (0.47) TSHRCA1CA2TRPV4MCL1
SCHEMBL20899391 0.76 TRPV4 (0.42) TSHRCA1CA2TRPV4MAOA
SCHEMBL19781773 0.76 CXCR2 (0.41) TSHRCA1CA2TRPV4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES TSHR 1592/4885CA1 3360/4885CA2 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.