Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711172 | 1.00 | ALOX15 (0.63) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL16050098 | 1.00 | ALOX15 (0.63) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| Bromide SCHEMBL16050013 | 0.99 | ALOX15 (0.61) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL19185954 | 0.90 | ALOX15 (0.54) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| Hydrochloric Acid SCHEMBL28510763 | 0.89 | ALOX15 (0.47) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL1215796 | 0.87 | ALOX15 (0.59) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL1215620 | 0.85 | ALOX15 (0.63) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13213955 | 0.84 | ALOX15 (0.69) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL1218968 | 0.83 | ALOX15 (0.57) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL1217379 | 0.83 | ALOX15 (0.60) | ALOX15ADRB2ADRA2ADRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521305-B | Novel high penetration drug for treating Parkinson disease and pharmaceutical composition thereof | 苏州泰飞尔医药有限公司 | 2023-04-25 | — | — | CN | disclosed |