Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025898 | 1.00 | DHODH (1.00) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4022761 | 1.00 | DHODH (1.00) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4025228 | 1.00 | DHODH (1.00) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL24727760 | 0.91 | DHODH (0.84) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4022932 | 0.89 | DHODH (0.80) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4254861 | 0.88 | DHODH (0.79) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31120774 | 0.87 | DHODH (0.76) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4022138 | 0.86 | DHODH (0.75) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4023145 | 0.85 | DHODH (0.74) | DHODHALOX15SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4022078 | 0.85 | DHODH (0.74) | DHODHALOX15SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245664-A1 | METHODS OF USING USP15 INHIBITORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2024-07-25 | — | — | US | disclosed |
| WO-2023039405-A1 | METHODS OF USING USP15 INHIBITORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2023-03-16 | — | — | WO | disclosed |