Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 20/20 | 0.84 |
| ▸ | LCK | P06239 | 2/20 | 0.61 |
| ▸ | BTK | Q06187 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
| ▸ | TEK | Q02763 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958052 | 1.00 | TNK2 (0.84) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL30338308 | 0.90 | TNK2 (0.87) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL2949506 | 0.90 | TNK2 (0.87) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL2955963 | 0.88 | TNK2 (0.70) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL30339004 | 0.88 | TNK2 (1.00) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL17859384 | 0.85 | TNK2 (0.88) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL13239773 | 0.79 | TNK2 (0.81) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL30338625 | 0.78 | TNK2 (1.00) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL30338621 | 0.75 | TNK2 (1.00) | TNK2LCKBTKKDRJAK3 | |
| SCHEMBL2955423 | 0.75 | TNK2 (0.76) | TNK2LCKBTKKDRJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039548-A1 | KINASE INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER | FRED HUTCHINSON CANCER CENTER (US) | 2023-03-16 | — | — | WO | disclosed |