Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339596 | 0.86 | PTGER1 (0.41) | THRBPDE4DKMT2AHTTMEN1 | |
| SCHEMBL30339630 | 0.85 | KMT2A (0.37) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL30339960 | 0.84 | MAPT (0.42) | THRBKMT2AHTTMEN1GAA | |
| SCHEMBL30339641 | 0.82 | KMT2A (0.51) | KMT2AHTTMEN1GAAALDH1A1 | |
| SCHEMBL30339514 | 0.80 | MAPT (0.42) | KMT2AHTTGAAALDH1A1KDM4E | |
| SCHEMBL30339802 | 0.80 | ALDH1A1 (0.45) | KMT2AHTTMEN1GAAALDH1A1 | |
| SCHEMBL30339611 | 0.79 | MAPT (0.46) | KMT2AHTTMEN1GAAALDH1A1 | |
| SCHEMBL30339763 | 0.79 | PTGER1 (0.44) | KMT2AHTTGAAALDH1A1KDM4E | |
| SCHEMBL30340291 | 0.79 | MAPT (0.42) | KMT2AHTTGAAALDH1A1KDM4E | |
| SCHEMBL30339554 | 0.79 | KDM4E (0.39) | KMT2AHTTGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003326-A | Synthesis method of trifluoromethyl indazole-containing derivative | 河南师范大学 | 2023-04-25 | — | — | CN | disclosed |