Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.48 |
| ▸ | PDCD1LG2 | Q9BQ51 | 18/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622942 | 1.00 | CD274 (0.48) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21623041 | 0.87 | CD274 (0.66) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21623395 | 0.82 | CD274 (0.43) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21622943 | 0.79 | CD274 (0.38) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30340393 | 0.79 | CD274 (0.38) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30340342 | 0.79 | PDCD1 (0.50) | CD274PDCD1 | |
| SCHEMBL21623099 | 0.74 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL30340553 | 0.73 | PDCD1 (0.45) | CD274PDCD1 | |
| SCHEMBL21623441 | 0.73 | PDCD1 (0.45) | CD274PDCD1 | |
| SCHEMBL30340392 | 0.72 | PDCD1 (0.39) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |