Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 15/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340553 | 0.84 | PDCD1 (0.45) | PDCD1CD274MEN1CYP1A2CYP2D6 | |
| SCHEMBL21623441 | 0.84 | PDCD1 (0.45) | PDCD1CD274MEN1CYP1A2CYP2D6 | |
| SCHEMBL30340633 | 0.83 | ALDH1A1 (0.38) | PDCD1CD274S1PR1CYP1A2TSHR | |
| SCHEMBL21622945 | 0.81 | CD274 (0.53) | PDCD1CD274 | |
| SCHEMBL30340399 | 0.81 | CD274 (0.48) | PDCD1CD274 | |
| SCHEMBL21623099 | 0.80 | CD274 (0.42) | PDCD1CD274 | |
| SCHEMBL21622942 | 0.79 | CD274 (0.48) | PDCD1CD274 | |
| SCHEMBL30340423 | 0.79 | CD274 (0.48) | PDCD1CD274 | |
| SCHEMBL21622950 | 0.79 | CD274 (0.39) | PDCD1CD274 | |
| SCHEMBL28472791 | 0.79 | CD274 (0.43) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |