Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068417 | 1.00 | GAA (0.61) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL22169101 | 0.87 | MAPT (0.57) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL30900463 | 0.87 | MAPT (0.57) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL2053813 | 0.85 | GAA (0.51) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL962246 | 0.85 | HTT (0.56) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL2012912 | 0.83 | HTT (0.59) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL2978442 | 0.83 | MAPT (0.47) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL22652075 | 0.83 | KDM4E (0.59) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL21448004 | 0.82 | SIRT6 (0.61) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL3598014 | 0.81 | SIRT6 (0.44) | GAAMAPTKDM4EPTK2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431239-A | Compounds, pharmaceutical compositions, kits and uses thereof | 密执安大学评议会 | 2025-02-14 | — | — | CN | disclosed |
| CN-113710241-B | Substituted bicyclic and tetracyclic quinones and related methods of use | 密执安大学评议会 | 2024-11-15 | — | — | CN | disclosed |
| EP-4402127-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL Business Ltd (GB) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023041905-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL BUSINESS LTD (GB) | 2023-03-23 | — | — | WO | disclosed |