Sugi Predict

Sugi Predict / Compounds / SCHEMBL30343345

SCHEMBL30343345

SCHEMBL30343345

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)C(C)C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 7/20 0.45
▸ OPRD1 P41143 7/20 0.45
▸ OPRK1 P41145 7/20 0.45
▸ GLP1R P43220 13/20 0.44
▸ SCTR P47872 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31461628 0.96 OPRM1 (0.45) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30884234 0.96 OPRM1 (0.44) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31255808 0.94 OPRM1 (0.43) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30836835 0.94 OPRM1 (0.40) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31461629 0.94 GLP1R (0.43) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30175817 0.94 OPRM1 (0.40) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31567827 0.93 GLP1R (0.44) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31175849 0.91 OPRM1 (0.39) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30242087 0.88 OPRM1 (0.42) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30882172 0.88 OPRM1 (0.44) OPRM1OPRD1OPRK1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124486-A1 GLP-1 RECEPTOR COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-06-19 — — WO disclosed
WO-2025092778-A1 GLP-1 COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-05-08 — — WO disclosed
CN-116120427-B Semex lattice Synthesis method of lupeptide 浙江九洲药业股份有限公司 2024-12-10 — — CN disclosed
CN-116120427-A Synthesis method of semaglutin 浙江九洲药业股份有限公司 2023-05-16 — — CN disclosed
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