SCHEMBL30344152

SCHEMBL30344152

CNCCOc1ccc(C)c(C(=O)NC2(c3cccc4ccccc34)CC2)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
PDK2 Q15119 2/20 0.39
KDM4E B2RXH2 3/20 0.38
GCGR P47871 1/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CXCR2 P25025 1/20 0.37
HRH1 P35367 1/20 0.37
HTR1A P08908 1/20 0.37
DRD2 P14416 1/20 0.37
HTR2A P28223 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155891 1.00 HTR1D (0.40) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL25155449 0.93 HTR1D (0.39) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL30344852 0.93 HTR1D (0.39) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL25155274 0.92 HTR1D (0.38) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL30344600 0.92 HTR1D (0.38) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL25155207 0.91 HTR1A (0.39) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL31360040 0.91 HTR1A (0.39) HTR1DHTR1BPDK2KDM4EGCGR
SCHEMBL25155451 0.91 KDM4E (0.47) PDK2KDM4EALDH1A1LMNA
SCHEMBL31360038 0.91 HTR1B (0.42) HTR1BGCGRCXCR2DRD2
SCHEMBL25155217 0.91 KDM4E (0.39) KDM4EGCGRCXCR2DRD2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD HTR1D 4269/4885HTR1B 3052/4885PDK2 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.