SCHEMBL30344366

SCHEMBL30344366

COC(=O)c1cc(OC2CN(C(=O)OC(C)(C)C)C2)ccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 2/20 0.43
GPR119 Q8TDV5 3/20 0.41
ALDH1A1 P00352 1/20 0.41
EED O75530 1/20 0.41
RBBP4 Q09028 1/20 0.41
SUZ12 Q15022 1/20 0.41
EZH2 Q15910 1/20 0.41
AEBP2 Q6ZN18 1/20 0.41
PDE4B Q07343 5/20 0.40
NR1H2 P55055 1/20 0.40
CACNB4 O00305 1/20 0.39
CACNA1A O00555 1/20 0.39
CACNA1G O43497 1/20 0.39
CACNG3 O60359 1/20 0.39
CACNA1F O60840 1/20 0.39
CACNA1H O95180 1/20 0.39
CACNB3 P54284 1/20 0.39
CACNA2D1 P54289 1/20 0.39
CACNG7 P62955 1/20 0.39
CACNA1B Q00975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155694 1.00 USP30 (0.43) USP30GPR119ALDH1A1EEDRBBP4
SCHEMBL30344060 0.89 GPR119 (0.54) GPR119ALDH1A1EEDRBBP4SUZ12
SCHEMBL25155201 0.89 GPR119 (0.54) GPR119ALDH1A1EEDRBBP4SUZ12
SCHEMBL30344230 0.88 USP30 (0.47) USP30GPR119ALDH1A1PDE4BCACNB4
SCHEMBL25155490 0.88 USP30 (0.47) USP30GPR119ALDH1A1PDE4BCACNB4
SCHEMBL26689691 0.87 USP30 (0.42) USP30GPR119ALDH1A1EEDRBBP4
SCHEMBL26689697 0.87 HDAC1 (0.43) USP30GPR119ALDH1A1PDE4BNR1H2
SCHEMBL7399784 0.86 CA12 (0.46) USP30GPR119ALDH1A1EEDRBBP4
SCHEMBL7403357 0.85 PDE4B (0.47) USP30GPR119ALDH1A1PDE4BCACNB4
SCHEMBL13280074 0.82 EED (0.41) USP30GPR119ALDH1A1EEDRBBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD USP30 399/4885GPR119 3277/4885ALDH1A1 2460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.