SCHEMBL30344671

SCHEMBL30344671

COC(=O)c1cc(OCC2CCN2C(=O)OC(C)(C)C)ccc1C

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ ALOX5AP P20292 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ GPR119 Q8TDV5 2/20 0.38
▸ EED O75530 1/20 0.38
▸ RBBP4 Q09028 1/20 0.38
▸ SUZ12 Q15022 1/20 0.38
▸ EZH2 Q15910 1/20 0.38
▸ AEBP2 Q6ZN18 1/20 0.38
▸ NR1H2 P55055 1/20 0.37
▸ NR1H3 Q13133 1/20 0.37
▸ HDAC8 Q9BY41 3/20 0.37
▸ TP53 P04637 1/20 0.37
▸ CHRNB4 P30926 1/20 0.37
▸ CHRNA3 P32297 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25156046 1.00 LMNA (0.41) LMNANPSR1ALOX5APALDH1A1MEN1
SCHEMBL25155275 1.00 LMNA (0.41) LMNANPSR1ALOX5APALDH1A1MEN1
SCHEMBL31360013 1.00 LMNA (0.41) LMNANPSR1ALOX5APALDH1A1MEN1
SCHEMBL31360329 1.00 LMNA (0.41) LMNANPSR1ALOX5APALDH1A1MEN1
SCHEMBL25155242 1.00 LMNA (0.41) LMNANPSR1ALOX5APALDH1A1MEN1
SCHEMBL25155582 0.94 LMNA (0.46) LMNANPSR1ALOX5APMEN1KMT2A
SCHEMBL31359974 0.94 LMNA (0.46) LMNANPSR1ALOX5APMEN1KMT2A
SCHEMBL25156357 0.94 LMNA (0.46) LMNANPSR1ALOX5APMEN1KMT2A
SCHEMBL31360101 0.93 ALOX5AP (0.43) LMNANPSR1ALOX5APMEN1KMT2A
SCHEMBL25155946 0.93 ALOX5AP (0.43) LMNANPSR1ALOX5APMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD LMNA 627/4885NPSR1 380/4885ALOX5AP 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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