Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | UQCRB | P14927 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442501 | 1.00 | EGLN1 (0.64) | EGLN1KDM4EGAAMMP1MMP12 | |
| SCHEMBL30345434 | 0.88 | EGLN1 (0.52) | EGLN1KDM4EMMP1MMP2 | |
| SCHEMBL28449287 | 0.88 | EGLN1 (0.52) | EGLN1KDM4EMMP1MMP2 | |
| SCHEMBL28442587 | 0.88 | EGLN1 (0.64) | EGLN1KDM4EEGLN3MEN1MAPT | |
| SCHEMBL30345459 | 0.88 | EGLN1 (0.64) | EGLN1KDM4EEGLN3MEN1MAPT | |
| SCHEMBL30345405 | 0.85 | EGLN1 (0.66) | EGLN1KDM4EGAAMEN1HTT | |
| SCHEMBL30345366 | 0.85 | EGLN1 (0.66) | EGLN1GAAMMP1 | |
| SCHEMBL28442506 | 0.85 | EGLN1 (0.66) | EGLN1KDM4EGAAMEN1HTT | |
| SCHEMBL28439755 | 0.85 | EGLN1 (0.66) | EGLN1GAAMMP1 | |
| SCHEMBL28446135 | 0.82 | HDAC3 (0.53) | EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |