Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24414995 | 1.00 | TLR7 (0.42) | TLR7TLR8NCF1ADORA3ADORA2A | |
| SCHEMBL20968317 | 0.92 | PARP1 (0.41) | TLR7TLR8NCF1PARP1 | |
| SCHEMBL20968326 | 0.91 | TLR7 (0.41) | TLR7TLR8NCF1PARP1 | |
| SCHEMBL18268482 | 0.86 | TLR7 (0.41) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL9036182 | 0.85 | TLR7 (0.52) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL9038851 | 0.83 | PARP1 (0.57) | TLR7TLR8PARP1 | |
| SCHEMBL8600371 | 0.82 | TNKS2 (0.53) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL19475356 | 0.80 | RAD52 (0.43) | TLR7TLR8PARP1 | |
| SCHEMBL20968264 | 0.80 | TP53 (0.42) | TLR7PARP1 | |
| SCHEMBL20968370 | 0.80 | TERT (0.44) | TLR7TLR8NCF1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419112-A1 | IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER | Ohio State Innovation Foundation (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023070132-A1 | IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER | OHIO STATE INNOVATION FOUNDATION (US) | 2023-04-27 | — | — | WO | disclosed |