Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.63 |
| ▸ | VEGFA | P15692 | 4/20 | 0.63 |
| ▸ | FLT1 | P17948 | 4/20 | 0.63 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.63 |
| ▸ | TET3 | O43151 | 1/20 | 0.63 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.63 |
| ▸ | ASPH | Q12797 | 1/20 | 0.63 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.63 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.63 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.63 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.63 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.63 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031409 | 1.00 | EGLN1 (0.63) | EGLN1VEGFAFLT1EGLN3TET3 | |
| Acetic Acid SCHEMBL23501731 | 0.95 | EGLN1 (0.61) | EGLN1VEGFAFLT1EGLN3TET3 | |
| Glycine SCHEMBL28657486 | 0.92 | EGLN1 (0.65) | EGLN1VEGFAFLT1EGLN3TET3 | |
| Acetic Acid Methyl Ester SCHEMBL30471482 | 0.91 | EGLN1 (0.64) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL30514566 | 0.87 | EGLN1 (0.68) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL4370919 | 0.87 | EGLN1 (0.68) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL19393710 | 0.85 | EGLN1 (0.63) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL3031405 | 0.85 | EGLN1 (0.63) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL14152807 | 0.84 | EGLN1 (0.62) | EGLN1VEGFAFLT1EGLN3TET3 | |
| SCHEMBL22462719 | 0.83 | EGLN1 (0.60) | EGLN1VEGFAFLT1EGLN3TET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423367-B | Preparation method and application of phenylpyridine compound | 乳源东阳光药业有限公司 | 2023-06-09 | — | — | CN | claimed |
| US-12612367-B2 | Method for producing nitrogen-containing heteroarylcarboxamide acetic acid derivative | AKEBIA THERAPEUTICS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| CN-118414327-A | Pyridinamide compounds, compositions, and methods of use as selective PHD1 inhibitors | 阿克比治疗有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-111423367-B | Preparation method and application of phenylpyridine compound | 乳源东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-111423367-B | Preparation method and application of phenylpyridine compound | 乳源东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20230159462-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROARYLCARBOXAMIDE ACETIC ACID DERIVATIVE | KREOS CAPITAL VII (UK) LIMITED (GB) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612367-B2 | Method for producing nitrogen-containing heteroarylcarboxamide acetic acid derivative | DIMT1, HIF1A, HIF1AN | EGLN1 912/4885VEGFA 269/4885FLT1 2371/4885 |
| US-20230159462-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROARYLCARBOXAMIDE ACETIC ACID DERIVATIVE | DIMT1, DLAT, COASY | EGLN1 1247/4885VEGFA 747/4885FLT1 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.