Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26087977 | 1.00 | STAT3 (0.48) | STAT3PLCG2CA12CA9KCNQ2 | |
| SCHEMBL26087980 | 0.88 | KCNQ2 (0.43) | STAT3CA12CA9KCNQ2MAPK8 | |
| SCHEMBL26088010 | 0.88 | GAA (0.58) | STAT3PLCG2CA12CA9GAA | |
| SCHEMBL30345688 | 0.88 | GAA (0.58) | STAT3PLCG2CA12CA9GAA | |
| SCHEMBL26087963 | 0.85 | MEN1 (0.52) | STAT3PLCG2CA12CA9LMNA | |
| SCHEMBL26087758 | 0.85 | STAT3 (0.50) | STAT3PLCG2CA12CA9MAPK8 | |
| SCHEMBL26090491 | 0.85 | MEN1 (0.55) | STAT3PLCG2CA12CA9KCNQ2 | |
| SCHEMBL30345859 | 0.85 | MEN1 (0.55) | STAT3PLCG2CA12CA9KCNQ2 | |
| SCHEMBL30346053 | 0.83 | NLRP3 (0.56) | STAT3PLCG2CA12CA9MAPK8 | |
| SCHEMBL26087853 | 0.83 | NLRP3 (0.56) | STAT3PLCG2CA12CA9MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | claimed |
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | disclosed |