SCHEMBL3034699

SCHEMBL3034699

Oc1ccc(CC(Cl)(Cl)Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.58
ESR2 Q92731 7/20 0.52
ABAT P80404 1/20 0.46
BLM P54132 3/20 0.45
CA2 P00918 3/20 0.44
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
IDO1 P14902 2/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
SLC6A2 P23975 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTR3A P46098 1/20 0.42
BACE1 P56817 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16241814 0.78 ESR1 (0.57) ESR1ESR2ABATBLMCA2
SCHEMBL10179843 0.76 CA1 (0.39) ESR1CA2SLC6A2CA1
SCHEMBL11613799 0.76 ALDH1A1 (0.52) ALDH1A1SLC6A2KMT2AMEN1NPC1
SCHEMBL7109436 0.76 ESR1 (0.61) ESR1ESR2ABATBLMCA2
SCHEMBL3658885 0.76 SLC6A4 (0.56) KDM4EALDH1A1IDO1SLC6A2TAAR1
SCHEMBL4593278 0.75 ESR1 (0.59) ESR1ESR2ABATBLMCA2
SCHEMBL6766398 0.75 ESR1 (0.64) ESR1ESR2BLMALDH1A1SLC6A2
SCHEMBL2174894 0.74 ESR1 (0.58) ESR1ESR2ABATBLMCA2
SCHEMBL3034697 0.74 SLC6A2 (0.33) ESR1SLC6A2
SCHEMBL28444880 0.74 IDO1 (0.46) IDO1TAAR1NPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454349-A Cocktail type mixed receptor and application thereof in detecting endocrine disruptors 山东师范大学 2020-07-28 CN claimed
CN-111263689-B Method for introducing solids into a planetary roller extruder for producing heat-sensitive polymers 德莎欧洲股份公司 2022-08-23 CN disclosed
CN-111454349-B Cocktail type mixed receptor and application thereof in detecting endocrine disruptors 山东师范大学 2022-05-27 CN disclosed
CN-110884745-B Method for applying die-cut pieces to a surface and testing method therefor 德莎欧洲股份公司 2022-05-03 CN disclosed
CN-114381214-A Die-cut part, in particular for permanently closing a hole 德莎欧洲股份公司 2022-04-22 CN disclosed
CN-114013386-A Stamping part, in particular for permanently closed holes 德莎欧洲股份公司 2022-02-08 CN disclosed
CN-114008158-A Pressure-sensitive adhesive with high filler content 德莎欧洲股份公司 2022-02-01 CN disclosed
EP-3908618-A1 USE OF THERMALLY STABLE TERPENE-PHENOL RESINS tesa SE (DE) 2021-11-17 EP disclosed
CN-104342056-B Pressure sensitive adhesive 德莎欧洲股份公司 2021-11-05 CN disclosed
CN-110499117-B Die-cut part, in particular for permanently closing a hole 德莎欧洲股份公司 2021-10-08 CN disclosed
EP-1773797-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-04-18 EP disclosed
WO-2006014012-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-02-09 WO disclosed
US-20050272678-A1 BMP-6 estrogen responsive element and methods of use thereof WYETH 2005-12-08 US disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed
US-5639776-A CROP PESTICIDE; NONPHYTOTOXIC, KIDNEY BEANS, ORANGES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-17 US disclosed
EP-0751130-A1 4,5-DIHYDROPYRAZOLE-5-THIONE DERIVATIVES AND ACARICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-01-02 EP disclosed
US-5248432-A Flotation fluids for gyroscopes and accelerometers CHARLES STARK DRAPER LABORATORY, INC. (US) 1993-09-28 US disclosed
US-5177252-A High density flotation fluids and lubricants for inertial instruments THE CHARLES STARK DRAPER LABORATORY, INC. (US) 1993-01-05 US disclosed
US-4835304-A FLOTATION FLUIDS FOR INERTIAL INSTRUMENTS SUCH AS GYROSCOPESAD ACCELEROMETERS; HIGH VISCOSITY; HYDRAULIC FLUIDS CHARLES STARK DRAPER LABORATORY (US) 1989-05-30 US disclosed
EP-0015860-A1 Process for the preparation of polyglycidyl ethers of polyphenols RHONE-POULENC CHIMIE DE BASE (FR) 1980-09-17 EP disclosed