Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378294 | 1.00 | HRH4 (0.60) | HRH4HRH3GRIN2DGRIN3BCHRM1 | |
| Acetic Acid SCHEMBL27854053 | 0.91 | OPRD1 (0.60) | HRH4HRH3GRIN2DGRIN3BCHRM1 | |
| SCHEMBL1811254 | 0.83 | GRIN2D (0.57) | HRH4HRH3GRIN2DGRIN3BCHRM1 | |
| SCHEMBL465754 | 0.83 | GRIN2D (0.57) | HRH4GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL17095658 | 0.81 | GRIN2D (0.55) | HRH4GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL30988524 | 0.81 | GRIN2D (0.55) | HRH4GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL4172255 | 0.81 | GRIN2D (0.49) | HRH4HRH3GRIN2DGRIN3BCHRM1 | |
| SCHEMBL4180910 | 0.81 | GAA (0.51) | HRH4HRH3GRIN2DGRIN3BCHRM1 | |
| SCHEMBL10196855 | 0.80 | HRH4 (0.61) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18278961 | 0.79 | OPRD1 (0.54) | HRH3GRIN2DGRIN3BCHRM1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415818-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | disclosed |
| WO-2023064361-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |