Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 1.00 |
| ▸ | STAT3 | P40763 | 4/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811269 | 1.00 | TYK2 (1.00) | TYK2STAT3PDE4D | |
| SCHEMBL21811163 | 1.00 | TYK2 (1.00) | TYK2STAT3PDE4D | |
| SCHEMBL21887776 | 1.00 | TYK2 (1.00) | TYK2STAT3PDE4D | |
| SCHEMBL21887515 | 0.91 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL21811321 | 0.91 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL21811186 | 0.91 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL30349300 | 0.91 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL21887376 | 0.89 | TYK2 (0.81) | TYK2STAT3 | |
| SCHEMBL30349442 | 0.87 | TYK2 (0.77) | TYK2STAT3PDE4D | |
| SCHEMBL22342898 | 0.86 | TYK2 (0.77) | TYK2STAT3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638915-B | Pyrazolo [1,5-a ] pyrimidine-3-carboxamide derivatives for the treatment of psoriasis and systemic lupus erythematosus | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |