Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462100 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4ECTNNB1WNT3ALDLR | |
| SCHEMBL28642368 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4ECTNNB1WNT3ALDLR | |
| SCHEMBL21259802 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4ECYP3A4CYP1A2LMNA | |
| SCHEMBL21747406 | 0.74 | CTNNB1 (0.53) | ALDH1A1CTNNB1WNT3ALDLRSMN1; SMN2 | |
| SCHEMBL20897370 | 0.68 | CTNNB1 (0.56) | ALDH1A1CTNNB1WNT3ALDLRSMN1; SMN2 | |
| SCHEMBL23428914 | 0.67 | ALDH1A1 (0.49) | ALDH1A1KDM4ELDLRCYP3A4CYP1A2 | |
| SCHEMBL5373712 | 0.66 | ALDH1A1 (0.46) | ALDH1A1CTNNB1WNT3ALDLRSMN1; SMN2 | |
| SCHEMBL5373716 | 0.66 | ALDH1A1 (0.46) | ALDH1A1CTNNB1WNT3ALDLRSMN1; SMN2 | |
| SCHEMBL18604872 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KDM4ELDLRCYP3A4CYP1A2 | |
| SCHEMBL18623188 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KDM4ELDLRCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230092227-A1 | PREPARATION METHOD FOR SYNTHESIZING CHIRAL NICOTINE FROM CHIRAL TERT-BUTYLSULFENAMIDE | SHENZHEN ZINWI BIO-TECH CO., LTD (CN) | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230092227-A1 | PREPARATION METHOD FOR SYNTHESIZING CHIRAL NICOTINE FROM CHIRAL TERT-BUTYLSULFENAMIDE | DNMT1, MECP2, DNMT3A | ALDH1A1 2729/4885KDM4E 326/4885CTNNB1 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.