Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.48 |
| ▸ | MTOR | P42345 | 9/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ATR | Q13535 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 12/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406092 | 1.00 | PIK3CA (0.48) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL30349801 | 0.82 | EEF2K (0.48) | PIK3CA | |
| SCHEMBL30349870 | 0.82 | PRKDC (0.38) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL25436149 | 0.82 | PRKDC (0.38) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL25404789 | 0.82 | EEF2K (0.48) | PIK3CA | |
| SCHEMBL25407471 | 0.81 | HSD17B10 (0.62) | HSD17B10HPGDHTT | |
| SCHEMBL30349792 | 0.81 | HSD17B10 (0.62) | HSD17B10HPGDHTT | |
| SCHEMBL30635120 | 0.79 | PIK3CA (0.40) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL30349839 | 0.78 | PIK3CA (0.48) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL12791613 | 0.77 | HPGD (0.63) | PIK3CAMTORPRKDCHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867277-A | Novel fused heterocyclyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |