Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26350770 | 0.86 | PARP2 (0.42) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL26350873 | 0.86 | ALDH1A1 (0.40) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL29712772 | 0.86 | PARP2 (0.42) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL30534136 | 0.86 | ALDH1A1 (0.40) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL24478284 | 0.85 | HSD17B10 (0.50) | PIK3CAMTORATMATRPRKDC | |
| Hydrochloric Acid SCHEMBL29712721 | 0.85 | ALDH1A1 (0.39) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL24478629 | 0.85 | HSD17B10 (0.50) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL29712769 | 0.85 | HSD17B10 (0.50) | PIK3CAMTORATMATRPRKDC | |
| SCHEMBL29712759 | 0.85 | HSD17B10 (0.50) | PIK3CAMTORATMATRPRKDC | |
| Hydrochloric Acid SCHEMBL30534141 | 0.84 | HSD17B10 (0.49) | PIK3CAMTORATMATRPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | claimed |
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |