Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314513 | 1.00 | SLC22A12 (0.40) | SLC22A12ALDH1A1SMN1; SMN2KDM4EPTGS1 | |
| SCHEMBL20875307 | 0.84 | SLC22A12 (0.39) | SLC22A12ALDH1A1SMN1; SMN2KDM4EPTGS1 | |
| SCHEMBL30080735 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EHRH4HTR2B | |
| SCHEMBL786015 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EHRH4HTR2B | |
| SCHEMBL4307550 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3465354 | 0.73 | KDM5C (0.40) | HRH4 | |
| SCHEMBL7831945 | 0.72 | GBA1 (0.52) | SLC22A12ALDH1A1SMN1; SMN2KDM4EPTGS1 | |
| SCHEMBL254106 | 0.71 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL22306680 | 0.69 | GBA1 (0.53) | ALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL1530890 | 0.69 | BACE1 (0.46) | SLC22A12MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661387-B | Composition for treating pulmonary fibrosis | 维克图斯生物系统有限公司 | 2023-05-30 | — | — | CN | disclosed |