Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.44 |
| ▸ | PRKDC | P78527 | 6/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626249 | 1.00 | PIK3CD (0.44) | PIK3CDPRKDCRAD52PIK3CAPIK3CB | |
| SCHEMBL30353514 | 0.89 | MTOR (0.47) | PIK3CDRAD52PIK3CAPIK3CGAKT1 | |
| SCHEMBL25626250 | 0.89 | MTOR (0.47) | PIK3CDRAD52PIK3CAPIK3CGAKT1 | |
| SCHEMBL25626207 | 0.80 | RAD52 (0.44) | PIK3CDPRKDCRAD52PIK3CAPIK3CB | |
| SCHEMBL30353557 | 0.80 | RAD52 (0.44) | PIK3CDPRKDCRAD52PIK3CAPIK3CB | |
| SCHEMBL25269019 | 0.73 | ALDH1A1 (0.55) | PIK3CDPRKDCRAD52PIK3CAPIK3CB | |
| SCHEMBL30353541 | 0.73 | ALDH1A1 (0.55) | PIK3CDPRKDCRAD52PIK3CAPIK3CB | |
| SCHEMBL31547982 | 0.71 | PIK3CA (0.57) | PIK3CACYP11B2PIK3R1 | |
| SCHEMBL24099574 | 0.71 | PIK3CA (0.57) | PIK3CACYP11B2PIK3R1 | |
| SCHEMBL31547953 | 0.71 | PIK3CD (0.39) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118946360-A | Bicyclic heteroarenes and methods of use thereof | 奇尼塔公司 | 2024-11-12 | — | — | CN | disclosed |
| EP-4161523-A1 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Yumanity Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |