Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25382253 | 1.00 | HTT (0.58) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL30354971 | 0.84 | MAPT (0.56) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL30354888 | 0.84 | SMN1; SMN2 (0.56) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL25382559 | 0.84 | SMN1; SMN2 (0.56) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL25381995 | 0.82 | SMN1; SMN2 (0.67) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL30354840 | 0.82 | SMN1; SMN2 (0.67) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL30354811 | 0.82 | HTT (0.62) | HTTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL16592530 | 0.80 | GRM4 (0.63) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL29886344 | 0.80 | GRM4 (0.63) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL25382636 | 0.79 | RAB9A (0.61) | HTTHSD17B10SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |