Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814530 | 1.00 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12700208 | 0.85 | GAA (0.59) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30354941 | 0.84 | NPC1 (0.64) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27135419 | 0.84 | CYP1A2 (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6816692 | 0.84 | NPC1 (0.64) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30339281 | 0.84 | CYP1A2 (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30354938 | 0.84 | MAPT (0.55) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29151334 | 0.84 | MAPT (0.55) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29151308 | 0.83 | GAA (0.56) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7945619 | 0.82 | KCNMA1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |