Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151292 | 1.00 | LMNA (0.68) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL3570088 | 0.82 | LMNA (0.72) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL31504344 | 0.82 | LMNA (0.72) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL30354787 | 0.79 | LMNA (0.43) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL21835222 | 0.79 | KMT2A (0.51) | LMNAMAPTRAB9ANPSR1MEN1 | |
| SCHEMBL29151259 | 0.79 | LMNA (0.43) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL29151272 | 0.78 | SMN1; SMN2 (0.46) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL30354876 | 0.78 | SMN1; SMN2 (0.46) | LMNACYP19A1MAPTRAB9ANPSR1 | |
| SCHEMBL30354934 | 0.76 | MAOB (0.49) | MAPTRAB9AMEN1KMT2AMAOB | |
| SCHEMBL29151257 | 0.76 | LMNA (0.64) | LMNACYP19A1MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |