SCHEMBL303553

SCHEMBL303553

O=[C]N(C1CCCCC1)C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 9/20 0.40
ADH1C P00326 6/20 0.39
ADH4 P08319 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ADH1B P00325 1/20 0.34
FDPS P14324 1/20 0.34
PHGDH O43175 2/20 0.32
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14855292 1.00 ADH1A (0.40) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL10013012 1.00 ADH1A (0.40) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL8745529 1.00 ADH1A (0.40) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL10012568 1.00 ADH1A (0.40) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL10913205 1.00 ADH1A (0.40) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL5122415 0.97 ADH1A (0.44) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL3160126 0.97 ADH1A (0.39) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL14855664 0.97 ADH1A (0.39) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL6005192 0.94 ADH1A (0.42) ADH1AADH1CADH4ALDH1A1ADH1B
SCHEMBL4496316 0.94 ADH1A (0.36) ADH1AADH1CADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752452-B1 Hydroxyquinolone-monoazo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-09-12 EP claimed
US-5760197-A YELLOW PIGMENT FOR DYEING TEXTILES DYSTAR JAPAN LTD. (JP) 1998-06-02 US claimed
EP-0752452-A1 Hydroxyquinolone-monoazo dyes, their preparation and use DyStar Japan Ltd. (JP) 1997-01-08 EP claimed
EP-0152759-B1 AMINOISOTHIAZOLE COMPOUNDS BASF Aktiengesellschaft (DE) 1989-08-23 EP claimed
EP-0150034-B1 DERIVATIVES OF 2-AMINOTHIOPHENE BASF Aktiengesellschaft (DE) 1989-08-02 EP claimed
US-4785116-A Aminoisothiazole compounds BASF AKTIENGESELLSCHAFT (DE) 1988-11-15 US claimed
US-4640892-A STORAGE STABLE BASE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 1987-02-03 US claimed
WO-2024128000-A1 ISOPOLYOXOTUNGSTATE SALT COMPOUND, SOLVATE THEREOF OR MIXTURE OF SAID COMPOUND AND SOLVATE, AND METHOD FOR PRODUCING SAID COMPOUND, SOLVATE OR MIXTURE 東京応化工業株式会社 2024-06-20 WO disclosed
EP-4364739-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING KIDNEY INJURY, AND AUTOPHAGY ACTIVATOR OSAKA UNIVERSITY (JP) 2024-05-08 EP disclosed
US-11976062-B2 Benzisoxazole compound OSAKA UNIVERSITY (JP) 2024-05-07 US disclosed
WO-2024070432-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, POLARIZING PLATE, IMAGE DISPLAY DEVICE AND POLYMERIZABLE COMPOUND 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024070691-A1 LAMINATE, IMAGE DISPLAY DEVICE, OPTICAL DEVICE, AND HEAD-MOUNTED DISPLAY 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024043261-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME 日本化薬株式会社 2024-02-29 WO disclosed
US-4343811-A ATHEROSCLEROSIS BOEHRINGER INGELHEIM GMBH (DE) 1982-08-10 US disclosed
US-4252943-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-02-24 US disclosed
US-4225617-A PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1980-09-30 US disclosed
EP-0015523-A1 Indole derivatives, their preparation and their use for medicaments Dr. Karl Thomae GmbH (DE) 1980-09-17 EP disclosed
US-4217359-A HYPOTENSIVE E. R. SQUIBB & SONS, INC. (US) 1980-08-12 US disclosed
US-4183951-A PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1980-01-15 US disclosed
US-4074057-A HYPERLIPEMIA, DIABETES TAKEDA CHEMICAL CO., LTD. (JA) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11976062-B2 Benzisoxazole compound CBR1, CYP2S1, CYP2E1 ADH1A 714/4885ADH1C 1167/4885ADH4 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.