SCHEMBL30356285

SCHEMBL30356285

O=C(F)c1cc([N+](=O)[O-])ccc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
MAPT P10636 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP3A4 P08684 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
ALOX15 P16050 1/20 0.45
KMT2A Q03164 3/20 0.44
PTPRC P08575 1/20 0.43
S100A4 P26447 1/20 0.43
HPGD P15428 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TP53 P04637 2/20 0.42
HTT P42858 1/20 0.42
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
GPR35 Q9HC97 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136718 0.84 ALDH1A1 (0.59) ALDH1A1MAPTCYP3A4TDP1ALOX15
SCHEMBL29695698 0.82 MAPK1 (0.52) ALDH1A1MAPTL3MBTL1CYP3A4TDP1
SCHEMBL4638377 0.82 KMT2A (0.60) ALDH1A1CYP3A4TDP1ALOX15KMT2A
SCHEMBL450293 0.82 ALDH1A1 (0.52) ALDH1A1MAPTL3MBTL1CYP3A4TDP1
SCHEMBL4009107 0.82 MAPK1 (0.52) ALDH1A1MAPTL3MBTL1CYP3A4TDP1
Hydrochloric Acid SCHEMBL5875909 0.82 ALDH1A1 (0.57) ALDH1A1MAPTCYP3A4TDP1ALOX15
SCHEMBL16960662 0.80 ALDH1A1 (0.47) ALDH1A1MAPTL3MBTL1CYP3A4TDP1
SCHEMBL8398518 0.79 ALDH1A1 (0.43) ALDH1A1MAPTL3MBTL1CYP3A4TDP1
SCHEMBL527397 0.78 ALDH1A1 (0.52) ALDH1A1MAPTL3MBTL1KMT2AHTT
SCHEMBL27967955 0.78 MAPT (0.53) ALDH1A1MAPTL3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174761-B Fluorination method 三明市海斯福化工有限责任公司 2023-03-24 CN disclosed