Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23304909 | 1.00 | KDM4E (0.57) | KDM4ECHEK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30358107 | 0.81 | KEAP1 (0.45) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL29010572 | 0.81 | KEAP1 (0.45) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL2158555 | 0.78 | KDM4E (0.58) | KDM4ECHEK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31347077 | 0.78 | KDM4E (0.58) | KDM4ECHEK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30540667 | 0.77 | NQO2 (0.46) | KDM4ECHEK1ALDH1A1MAPTNR4A2 | |
| SCHEMBL20541577 | 0.76 | CHEK1 (0.50) | CHEK1PIM3PIM1NR4A2RXFP1 | |
| SCHEMBL16506119 | 0.75 | KDM4E (0.41) | KDM4ECHEK1ALDH1A1SMN1; SMN2PIM3 | |
| SCHEMBL30668122 | 0.75 | CD38 (0.41) | KDM4ECHEK1ALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL20542164 | 0.74 | PIM3 (0.44) | CHEK1SMN1; SMN2PIM3PIM1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| CN-116041344-A | Bicyclic heteroaryl carboxamide compounds as SOS1 inhibitors | 北京望实智慧科技有限公司 | 2023-05-02 | — | — | CN | disclosed |