Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 1.00 |
| ▸ | ALDH1A3 | P47895 | 9/20 | 1.00 |
| ▸ | ALDH1A2 | O94788 | 10/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747369 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2MEN1KMT2A | |
| SCHEMBL30358130 | 0.92 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2MEN1KMT2A | |
| SCHEMBL19747626 | 0.92 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2MEN1KMT2A | |
| SCHEMBL21271718 | 0.90 | ALDH1A1 (0.86) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL30358106 | 0.90 | ALDH1A1 (0.86) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL30358104 | 0.90 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2MEN1KMT2A | |
| SCHEMBL19746950 | 0.90 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2MEN1KMT2A | |
| SCHEMBL21271745 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL30358135 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL19746114 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | claimed |
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | disclosed |