SCHEMBL30358232

SCHEMBL30358232

Nc1ccc(/C=C/c2ccc3ccccc3c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.73
CYP3A4 P08684 3/20 0.63
CYP19A1 P11511 5/20 0.61
MAOA P21397 2/20 0.61
MAOB P27338 2/20 0.61
ALDH1A1 P00352 3/20 0.59
MAPT P10636 2/20 0.59
GLA P06280 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MEN1 O00255 1/20 0.59
NPC1 O15118 1/20 0.59
CASP3 P42574 1/20 0.59
RAB9A P51151 1/20 0.59
KMT2A Q03164 1/20 0.59
ATM Q13315 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
PTGS1 P23219 1/20 0.58
HSD17B10 Q99714 2/20 0.58
NQO2 P16083 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10892919 0.91 CYP19A1 (0.62) RELACYP3A4CYP19A1MAOAMAOB
SCHEMBL10892923 0.91 CYP19A1 (0.62) RELACYP3A4CYP19A1MAOAMAOB
SCHEMBL29842519 0.87 RELA (0.86) RELACYP3A4ALDH1A1MAPTGLA
SCHEMBL5552162 0.87 RELA (0.86) RELACYP3A4ALDH1A1MAPTGLA
SCHEMBL5050698 0.87 RELA (0.86) RELACYP3A4ALDH1A1MAPTGLA
SCHEMBL5552166 0.87 RELA (0.86) RELACYP3A4ALDH1A1MAPTGLA
SCHEMBL5050695 0.87 RELA (0.86) RELACYP3A4ALDH1A1MAPTGLA
SCHEMBL13304744 0.86 RELA (0.70) RELACYP3A4CYP19A1MAOAMAOB
SCHEMBL29966849 0.86 RELA (0.70) RELACYP3A4CYP19A1MAOAMAOB
SCHEMBL28889113 0.86 RELA (0.70) RELACYP3A4CYP19A1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4412598-A1 TEMPERATURE PROGRAMMABLE SMALL MOLECULES FOR THERMORESPONSIVE SMART WINDOWS AND APPLICATIONS THEREOF Council Of Scientific & Industrial Research (IN) 2024-08-14 EP disclosed
WO-2023058048-A1 TEMPERATURE PROGRAMMABLE SMALL MOLECULES FOR THERMORESPONSIVE SMART WINDOWS AND APPLICATIONS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2023-04-13 WO disclosed