Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318334 | 1.00 | KDM4E (0.50) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28319461 | 0.87 | KDM4E (0.68) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23176649 | 0.87 | KDM4E (0.53) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23176468 | 0.86 | KDM4E (0.46) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30358397 | 0.82 | GRK6 (0.42) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30358398 | 0.81 | NPC1 (0.46) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28876443 | 0.81 | NPC1 (0.46) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11328720 | 0.81 | KDM4E (0.58) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11332226 | 0.81 | KDM4E (0.73) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30358390 | 0.81 | GRK6 (0.41) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105300-B | Method for synthesizing 2-trifluoroethyl substituted benzoxazole compound | 福州大学 | 2023-04-14 | — | — | CN | disclosed |