Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30358557 | 0.98 | PARP1 (0.39) | PARP1MKNK2ENPP1ENPP3P2RX7 | |
| SCHEMBL31365162 | 0.84 | ENPP3 (0.38) | PARP1MKNK2ENPP1ENPP3IRAK4 | |
| SCHEMBL30319582 | 0.82 | PARP1 (0.58) | PARP1MKNK2MKNK1SLC22A12 | |
| Hydrochloric Acid SCHEMBL30319541 | 0.81 | PARP1 (0.57) | PARP1MKNK2MKNK1SLC22A12 | |
| SCHEMBL29665757 | 0.80 | MKNK2 (0.41) | PARP1MKNK2ENPP1ENPP3IRAK4 | |
| SCHEMBL4417290 | 0.80 | MKNK2 (0.41) | PARP1MKNK2ENPP1ENPP3IRAK4 | |
| SCHEMBL30564558 | 0.79 | NOTUM (0.43) | PARP1MKNK2IRAK4MKNK1SLC22A12 | |
| SCHEMBL30358554 | 0.79 | ENPP3 (0.35) | PARP1MKNK2ENPP1ENPP3IRAK4 | |
| SCHEMBL30172790 | 0.78 | MKNK2 (0.40) | PARP1MKNK2IRAK4MKNK1SLC22A12 | |
| Hydrochloric Acid SCHEMBL30358580 | 0.74 | MKNK2 (0.39) | PARP1MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4181963-A1 | DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF | Coval Biopharma (Shanghai) Co., Ltd. (CN) | 2023-05-24 | — | — | EP | disclosed |