Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192416 | 1.00 | GPR52 (0.47) | GPR52EGFRPTPN1S1PR1KMT2A | |
| SCHEMBL28670082 | 1.00 | GPR52 (0.47) | GPR52EGFRPTPN1S1PR1KMT2A | |
| SCHEMBL16191618 | 0.88 | TDP1 (0.51) | GPR52KMT2ATP53CYP3A4MAPT | |
| SCHEMBL30358568 | 0.88 | TDP1 (0.51) | GPR52KMT2ATP53CYP3A4MAPT | |
| SCHEMBL28656810 | 0.88 | TDP1 (0.51) | GPR52KMT2ATP53CYP3A4MAPT | |
| SCHEMBL16290727 | 0.88 | PTPN1 (0.46) | PTPN1S1PR1KMT2ATP53CYP3A4 | |
| SCHEMBL30358578 | 0.80 | MAPT (0.57) | KMT2ATP53CYP3A4MAPTATM | |
| SCHEMBL16191546 | 0.80 | MAPT (0.57) | KMT2ATP53CYP3A4MAPTATM | |
| SCHEMBL16191542 | 0.80 | MAPT (0.57) | KMT2ATP53CYP3A4MAPTATM | |
| SCHEMBL16191441 | 0.80 | FLT3 (0.47) | KMT2ACYP3A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521048-B | Application of polysubstituted benzene compound in preparation of medicine for treating cognitive disorder diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2023-04-14 | — | — | CN | disclosed |