Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | NPY1R | P25929 | 3/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | NPY4R | P50391 | 1/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.60 |
| ▸ | APLNR | P35414 | 1/20 | 0.57 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367784 | 0.86 | NTSR2 (0.62) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL30638358 | 0.82 | GRB2 (0.58) | OPRD1OPRM1OPRK1APLNRNTSR2 | |
| SCHEMBL5710757 | 0.81 | NPY1R (0.56) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL5710761 | 0.81 | NPY1R (0.56) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL30498025 | 0.80 | OPRM1 (0.53) | OPRD1OPRM1OPRK1NPY1R | |
| SCHEMBL1247726 | 0.80 | GRB2 (0.61) | APLNRNTSR2NTSR1CAPN1 | |
| SCHEMBL29362706 | 0.80 | GRB2 (0.67) | APLNRNTSR2NTSR1CAPN1SORT1 | |
| SCHEMBL30498028 | 0.80 | OPRM1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31291033 | 0.79 | NPY1R (0.60) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL29611384 | 0.78 | NMUR2 (0.51) | OPRD1OPRM1OPRK1APLNRCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240401076-A1 | SELF-REPLICATING RNA MOLECULES AND APPLICATION THEREOF | R&R THERAPEUTICS INC. (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-115960922-A | Self-replicating RNA molecule design and uses thereof | 吴可行 | 2023-04-14 | — | — | CN | disclosed |
| WO-2023056980-A1 | DESIGN OF SELF-REPLICATING RNA MOLECULES AND APPLICATION THEREOF | 吴可行 | 2023-04-13 | — | — | WO | disclosed |