Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359070 | 0.81 | HTT (0.55) | KMT2ACYP2C9CYP2C19MAPK14HTT | |
| SCHEMBL30359092 | 0.78 | HTT (0.58) | KMT2ATSHRCYP2C9CYP2C19MAPK14 | |
| SCHEMBL4788243 | 0.76 | TSHR (0.53) | MEN1KMT2ATSHRCYP2C9CYP2C19 | |
| SCHEMBL4788064 | 0.76 | TSHR (0.53) | MEN1KMT2ATSHRCYP2C9CYP2C19 | |
| SCHEMBL30334082 | 0.76 | MEN1 (0.61) | MEN1KMT2ATSHRCYP2C9CYP2C19 | |
| SCHEMBL31454273 | 0.76 | TSHR (0.62) | MEN1KMT2ATSHRHSD11B1ALDH1A1 | |
| SCHEMBL11715149 | 0.76 | TSHR (0.80) | MEN1KMT2ATSHRCYP2C9CYP2C19 | |
| SCHEMBL22305400 | 0.76 | TSHR (0.80) | MEN1KMT2ATSHRCYP2C9CYP2C19 | |
| SCHEMBL17793825 | 0.76 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL23536584 | 0.75 | TSHR (0.61) | MEN1KMT2ATSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |