Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788243 | 1.00 | TSHR (0.53) | TSHRHTTMEN1KMT2AHCRTR1 | |
| SCHEMBL4635455 | 0.82 | LMNA (0.57) | TSHRHTTKMT2AHCRTR1HCRTR2 | |
| SCHEMBL4636549 | 0.81 | CPS1 (0.53) | HTTMEN1KMT2AMAPK14KDM4E | |
| SCHEMBL4635407 | 0.80 | CYP2C9 (0.52) | CYP2C9CYP2C19MAPK14HSD11B1LMNA | |
| SCHEMBL4636613 | 0.79 | CES2 (0.46) | TSHRHCRTR1HCRTR2 | |
| SCHEMBL4636532 | 0.79 | P2RX7 (0.46) | TSHRHCRTR1HCRTR2ALDH1A1HSD11B1 | |
| SCHEMBL4636539 | 0.79 | TSHR (0.46) | TSHRHCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL5390608 | 0.78 | MEN1 (0.58) | TSHRHTTMEN1KMT2ACYP2C9 | |
| SCHEMBL17946287 | 0.77 | MEN1 (0.65) | TSHRHTTMEN1KMT2ACYP2C9 | |
| SCHEMBL22305400 | 0.77 | TSHR (0.80) | TSHRHTTMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |