Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359287 | 1.00 | EGFR (0.36) | EGFRLPLLIPG | |
| SCHEMBL21410690 | 1.00 | EGFR (0.36) | EGFRLPLLIPG | |
| SCHEMBL16047825 | 0.84 | EGFR (0.39) | EGFRLPLLIPG | |
| SCHEMBL31265045 | 0.84 | EGFR (0.39) | EGFRLPLLIPG | |
| SCHEMBL31302110 | 0.84 | EGFR (0.36) | EGFR | |
| SCHEMBL4733734 | 0.83 | EGFR (0.31) | EGFR | |
| SCHEMBL30796761 | 0.78 | JAK2 (0.37) | EGFRLPLLIPG | |
| SCHEMBL26598153 | 0.78 | EGFR (0.35) | EGFRLPLLIPG | |
| SCHEMBL1477534 | 0.77 | LPL (0.42) | EGFRLPLLIPG | |
| SCHEMBL31183208 | 0.77 | LPL (0.42) | EGFRLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436665-A1 | HETEROCYCLIC SUBSTITUTED 1,3,4-THIADIAZOLE AND PYRIDAZINE COMPOUNDS AND METHODS OF USING THE SAME | Rgenta Therapeutics, Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023092149-A1 | HETEROCYCLIC SUBSTITUTED 1,3,4-THIADIAZOLE AND PYRIDAZINE COMPOUNDS AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |