Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 14/20 | 0.34 |
| ▸ | ATR | Q13535 | 14/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 14/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.34 |
| ▸ | ATM | Q13315 | 8/20 | 0.34 |
| ▸ | MTOR | P42345 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | SERPINA2 | P20848 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541910 | 0.83 | PRKDC (0.39) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL3994597 | 0.68 | SMN1; SMN2 (0.48) | CYP11B2CYP11B1GRM2 | |
| SCHEMBL20374457 | 0.67 | PRKDC (0.67) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL23269469 | 0.67 | KMT2A (0.46) | GRM2 | |
| SCHEMBL797783 | 0.66 | NPM1 (0.42) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL14247892 | 0.65 | TLR8 (0.40) | PIK3CBGRM2 | |
| SCHEMBL16196348 | 0.64 | CYP11B2 (0.51) | MTORCYP11B2CYP11B1GRM2 | |
| SCHEMBL796862 | 0.64 | PRKDC (0.55) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL2463549 | 0.63 | HTT (0.45) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL20037864 | 0.62 | CYP11B2 (0.41) | MTORCYP11B2CYP11B1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |