Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388537 | 1.00 | MAPT (0.71) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2389827 | 0.91 | MAPT (0.75) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1846466 | 0.90 | MAPT (0.82) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1841546 | 0.89 | MAPT (0.72) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1843801 | 0.86 | MAPT (0.70) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1842179 | 0.84 | MAPT (0.71) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1845699 | 0.84 | MAPT (0.70) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1844319 | 0.82 | MAPT (0.67) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1842419 | 0.82 | DCTPP1 (0.69) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1847097 | 0.82 | MAPT (0.82) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11568956-B2 | Methods for identifying inhibitors of amyloid protein aggregation | TREVENTIS CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |