Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977416 | 1.00 | TDP1 (0.67) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL2336609 | 0.80 | TDP1 (0.78) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL2972710 | 0.80 | TDP1 (1.00) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL30929832 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ACYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL10874071 | 0.79 | TDP1 (0.97) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL7760816 | 0.78 | TSHR (0.62) | TDP1MEN1KMT2ALMNATSHR | |
| SCHEMBL28977415 | 0.77 | POLB (0.48) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL30360234 | 0.77 | POLB (0.48) | TDP1RORCMEN1KMT2ACYP1A2 | |
| SCHEMBL30360235 | 0.76 | MAPT (0.51) | TDP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL28977413 | 0.76 | MAPT (0.51) | TDP1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894362-B | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-115894362-B | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115894362-A | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-04-04 | — | — | CN | disclosed |