Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360234 | 1.00 | POLB (0.48) | POLBKMT2AMEN1LMNATDP1 | |
| SCHEMBL11120482 | 0.89 | ALDH1A1 (0.47) | POLBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11120481 | 0.89 | ALDH1A1 (0.47) | POLBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10595968 | 0.84 | ALDH1A1 (0.46) | POLBKMT2AMEN1LMNATDP1 | |
| SCHEMBL11316740 | 0.82 | POLB (0.62) | POLBKMT2AMEN1LMNATDP1 | |
| SCHEMBL30929837 | 0.82 | MAPT (0.42) | POLBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28977418 | 0.80 | MEN1 (0.53) | POLBKMT2AMEN1LMNAHTT | |
| SCHEMBL30360239 | 0.80 | MEN1 (0.53) | POLBKMT2AMEN1LMNAHTT | |
| SCHEMBL30360237 | 0.77 | TDP1 (0.67) | KMT2AMEN1LMNATDP1RORC | |
| SCHEMBL28977416 | 0.77 | TDP1 (0.67) | KMT2AMEN1LMNATDP1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894362-B | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-115894362-A | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894362-B | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115894362-A | Intermediate and application and method thereof in preparation of pyrroloquinoline quinone | 山东原力泰医药科技有限公司 | 2023-04-04 | — | — | CN | disclosed |