SCHEMBL30360258

SCHEMBL30360258

Cc1cc(C)cc(-c2nccc3ccccc23)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.53
KDM4E B2RXH2 4/20 0.49
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
MAPT P10636 3/20 0.49
MAPK1 P28482 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2C19 P33261 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KMT2A Q03164 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4439497 1.00 CYP2A6 (0.53) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL30011331 0.98 CYP2A6 (0.52) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL5468265 0.96 CYP2A6 (0.53) CYP2A6KDM4ENPC1RAB9AMAPT
Hydrochloric Acid SCHEMBL6007561 0.95 CYP2A6 (0.52) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL14341091 0.89 CYP2A6 (0.46) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL11976467 0.86 KMT2A (0.50) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL24795587 0.86 CYP2A6 (0.44) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL27085341 0.85 CYP2A6 (0.46) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL11976472 0.84 CYP2A6 (0.52) CYP2A6KDM4ENPC1RAB9AMAPT
SCHEMBL3142955 0.84 ALDH1A1 (0.65) CYP2A6KDM4ENPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110229192-B Deuterated iridium complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2023-04-18 CN claimed
CN-117535046-A Luminescent material composition and application thereof 北京燕化集联光电技术有限公司 2024-02-09 CN disclosed
CN-111961089-B Organometallic complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2023-10-31 CN disclosed
CN-110229192-B Deuterated iridium complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2023-04-18 CN disclosed