SCHEMBL30360368

SCHEMBL30360368

Brc1ccccc1-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
MAPK1 P28482 3/20 0.73
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
RAB9A P51151 4/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TP53 P04637 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
MCL1 Q07820 1/20 0.39
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21202807 1.00 ALDH1A1 (0.73) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL21037629 1.00 ALDH1A1 (0.73) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL9762542 0.90 ALDH1A1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL29687904 0.90 ALDH1A1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL30046055 0.88 MAPK1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL16617019 0.88 MAPK1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL19107130 0.88 MAPK1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL29934895 0.88 MAPK1 (0.70) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL18015368 0.87 ALDH1A1 (0.61) ALDH1A1MAPK1CRHBPCRHR2RAB9A
SCHEMBL18015575 0.87 ALDH1A1 (0.61) ALDH1A1MAPK1CRHBPCRHR2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199585-A Light-emitting device and amine compound for light-emitting device 三星显示有限公司 2023-06-02 CN disclosed