SCHEMBL30360441

SCHEMBL30360441

CCC(N)c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 7/20 0.50
KCNH2 Q12809 1/20 0.50
TSHR P16473 1/20 0.48
KCNE1 P15382 2/20 0.47
CYP2D6 P10635 1/20 0.47
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
CHRM2 P08172 1/20 0.42
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3465329 1.00 KCNA5 (0.50) KCNA5KCNH2TSHRKCNE1CYP2D6
SCHEMBL30682711 1.00 KCNA5 (0.50) KCNA5KCNH2TSHRKCNE1CYP2D6
SCHEMBL311511 1.00 KCNA5 (0.50) KCNA5KCNH2TSHRKCNE1CYP2D6
SCHEMBL1579392 1.00 KCNA5 (0.50) KCNA5KCNH2TSHRKCNE1CYP2D6
Hydrochloric Acid SCHEMBL6776168 0.98 KCNA5 (0.49) KCNA5KCNH2TSHRKCNE1CYP2D6
Hydrochloric Acid SCHEMBL6081585 0.98 KCNA5 (0.49) KCNA5KCNH2TSHRKCNE1CYP2D6
Ammonia Solution, Strong SCHEMBL7426262 0.98 KCNA5 (0.49) KCNA5KCNH2TSHRKCNE1CYP2D6
Hydrochloric Acid SCHEMBL7929348 0.98 KCNA5 (0.49) KCNA5KCNH2TSHRKCNE1CYP2D6
Hydrochloric Acid SCHEMBL6771556 0.98 KCNA5 (0.49) KCNA5KCNH2TSHRKCNE1CYP2D6
Hypochlorous Acid SCHEMBL20677392 0.94 KCNA5 (0.46) KCNA5KCNH2TSHRKCNE1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
WO-2024182736-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME SIONNA THERAPEUTICS INC. (US) 2024-09-06 WO disclosed
CN-114072207-B Bicyclic compounds 维瓦斯治疗公司 2024-03-29 CN disclosed
CN-115894447-A METTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2023-04-04 CN disclosed